DEEPER INSIGHTS, SMARTER CURESTM

We translate genomic intelligence into multi-targeting therapies

THE PARADIGM SHIFT

CURING POLYGENIC DISEASES REQUIRES SMARTER MULTI-TARGETED THERAPIES

DEEPER INSIGHTS INTO TARGET COMBINATIONS: Our unique ExpansiveAI cognitive computing system helps us aggregate, model, and mine large biomedical datasets. This has empowered us to discover novel combinations of genomic changes that interact to drive complex disease states.

SMARTER DRUG DESIGN: Our proprietary Arromer RNA therapeutic platform then empowers us to rapidly translate these genomic insights to design, test, and build single agent multi-targeting RNA drugs that are capable of effectively blocking multiple disease mechanisms simultaneously.

CORE VALUES

IMAGINATION

INNOVATION

INTEGRITY

PLATFORM TECHNOLOGIES

DEEPER INSIGHTS: Our unique ExpansiveAI cognitive computing system empowered our systems biologists to integrate, model, and to use machine learning to mine complex genomic and biomedical datasets to uncover novel targeting combinations that can drive complex disease mechanisms and therapy resistance.  We then translate that genomic intelligence into single agent multi-modal combinatorial targeting drugs using our proprietary Arromer RNA therapeutic platform.

SMARTER CURES: Arromers are single agent chemically modified RNA oligonucleotides with a proprietary bivalent chimeric structure, which combines the precise selectivity of dual aptamer directed binding with the power and flexibility of multiple siRNA to silence the right combination of target genes in the right cell types.  The Arromer technology has next generation pharmacological properties and multi-targeting features which make it a best in class therapeutic modality to address many unmet needs for complex multigenic diseases.

SO has developed state of the art bioengineering laboratory infrastructure to industrialize this new platform in order to drive multiple pre-clinical Arromer programs into the clinic. Our goal is to advance multiple innovative Arromer therapies through development and to market in the next 5 years.

  • Mine

    Discover new mechanistic insights in complex diseases

  • Design

    Turn genomic intelligence into multi-targeting strategies

  • Engineer

    Arromers are synthesized, tested, and optimized to select clinical leads

  • Develop

    IND enabling studies and clinical development

  • Commercialize

    Focus on unmet needs

Leadership

Industry Innovators with Deep Experience

The board

Scientific Advisory Board

PARTNERSHIP OPPORTUNITIES

We welcome opportunities to collaborate with leading pharmaceutical companies to advance innovative multi-targeting therapies. Please email us to schedule an introductory meeting: cvillani@systemsoncology.com.

CAREERS FOR CANCER WARRIORS

At Systems Oncology, we provide a collaborative environment, excellent benefits, and exciting training opportunities for professionals to thrive and grow. Apply today if you are interested in the development of innovative cancer therapeutics!

Apply today

Open positions

Director of Drug Development

Scottsdale, Arizona (preferred)

Patent Agent

Scottsdale, Arizona (preferred)

AI Research Fellowship

Scottsdale, Arizona

Cancer Therapeutics Scientist

Scottsdale, Arizona

SOFTWARE ENGINEER

Scottsdale, Arizona

SYSTEMS BIOLOGIST

Scottsdale, Arizona

Research Associate II-III

Scottsdale, Arizona

Research Scientist I-III, R&D

Scottsdale, Arizona

CONTACT SYSTEMS ONCOLOGY

7201 E. Henkel Way, Suite 205, Scottsdale, AZ 85255

CVILLANI@SYSTEMSONCOLOGY.COM